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What are the causes of disease? - OCR 21st CenturyPathogens causing disease in animals and plants

Diseases are abnormal conditions that affect an organism鈥檚 body, organs, tissues or cells. Some are caused by pathogens, and organisms have defences to them.

Part of Biology (Single Science)Keeping healthy

Main disease-causing organisms (pathogens) in animals and plants

are disease-causing , , or . All organisms are affected by pathogens. Even bacteria can be infected by certain types of virus.

There are four main types of pathogen.

PathogenWidth (渭m)Example in animalsExample in plants
Viruses 0.02 - 0.3HIV potentially leading to AIDSTobacco mosaic virus
Bacteria1 - 5SalmonellaAgrobacterium
Protists1 +MalariaDowny mildew
Fungi50 +Athlete's footBlack rose spot
PathogenViruses
Width (渭m) 0.02 - 0.3
Example in animalsHIV potentially leading to AIDS
Example in plantsTobacco mosaic virus
PathogenBacteria
Width (渭m)1 - 5
Example in animalsSalmonella
Example in plantsAgrobacterium
PathogenProtists
Width (渭m)1 +
Example in animalsMalaria
Example in plantsDowny mildew
PathogenFungi
Width (渭m)50 +
Example in animalsAthlete's foot
Example in plantsBlack rose spot

For comparison a human hair is 17 - 18 渭m across.

All types of pathogen have a simple life cycle. They infect a host, reproduce themselves - or replicate themselves if they are a virus - spread from their and infect other . They all have structural that make them successful at completing their life cycles, enabling them to cause further disease.

Bacteria, fungi and protists can reproduce wherever the conditions are warm, with plenty of moisture, nutrients, and space. Viruses can only reproduce by invading living cells.

VirusBacteriaProtistFungus
Prokaryote or eukaryoteNeitherProkaryoteEukaryoteEukaryote
DNA locationIn a protein shellCell cytoplasmNucleusNucleus
Single-celled or multicellularNeither (non-cellular). Can only reproduce inside another living cell.Single-celledSingle-celled or multicellularMostly multicellular but some are single-celled
Prokaryote or eukaryote
VirusNeither
BacteriaProkaryote
ProtistEukaryote
FungusEukaryote
DNA location
VirusIn a protein shell
BacteriaCell cytoplasm
ProtistNucleus
FungusNucleus
Single-celled or multicellular
VirusNeither (non-cellular). Can only reproduce inside another living cell.
BacteriaSingle-celled
ProtistSingle-celled or multicellular
FungusMostly multicellular but some are single-celled

Diseases caused by pathogens are called . This means they can be transferred from one organism to another.

There are other types of disease that cannot be caught:

  1. inherited genetic disorders like
  2. that are caused by a lack of essential vitamins or , eg , which occurs when an individual has insufficient vitamin C
  3. diseases like cancer that develop as a result of exposure to or develop naturally as cell division occurs incorrectly

Disease transmission

of pathogens can occur in a number of important ways.

Type of transmissionExamples
Direct contactThis can be sexual contact during intercourse or non-sexual contact, eg shaking hands.
WaterDirty water can transmit many diseases, such as the cholera bacterium.
AirWhen a person who is infected by the common cold sneezes, they spray thousands of tiny droplets containing virus particles, which can infect others.
Unhygienic food preparationUndercooked or reheated food can cause bacterial diseases like Salmonella food poisoning.
VectorMalaria is spread by mosquitoes. Any organism that can spread a disease is called a vector.
Type of transmissionDirect contact
ExamplesThis can be sexual contact during intercourse or non-sexual contact, eg shaking hands.
Type of transmissionWater
ExamplesDirty water can transmit many diseases, such as the cholera bacterium.
Type of transmissionAir
ExamplesWhen a person who is infected by the common cold sneezes, they spray thousands of tiny droplets containing virus particles, which can infect others.
Type of transmissionUnhygienic food preparation
ExamplesUndercooked or reheated food can cause bacterial diseases like Salmonella food poisoning.
Type of transmissionVector
ExamplesMalaria is spread by mosquitoes. Any organism that can spread a disease is called a vector.

Causing symptoms

Pathogens cause symptoms by:

  1. releasing
  2. damaging cells by invading and reproducing

It takes a while for pathogens to cause symptoms after they have infected an organism. This is because the symptoms only appear when there is a very large number of pathogens present. The time taken between infection and the appearance of symptoms is called the incubation period.

The incubation period can last for a few hours or even several years, depending on the pathogen. As they are not showing symptoms, the host organism can appear healthy.