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What are the causes of disease? - OCR 21st CenturyExamples of diseases

Diseases are abnormal conditions that affect an organism鈥檚 body, organs, tissues or cells. Some are caused by pathogens, and organisms have defences to them.

Part of Biology (Single Science)Keeping healthy

Examples of diseases

Viral diseases

are not considered to be living organisms because they do not complete all of the seven life processes: movement, respiration, sensitivity, nutrition, excretion, reproduction and growth. This means they can only reproduce by invading living cells.

We say 'strains' of virus and not species. A strain is made up of a genetic material core, , which is surrounded by a protein coat.

Scientific illustration of the hepatatis virus
Image caption,
A structure of a hepatitis virus, depicting the DNA core coloured blue and protein coat as pink

Viral infections cannot be treated by .

Influenza (flu)

Influenza viruses are spread in droplets of body fluids from coughs and sneezes. The droplets are inhaled or transferred by hand to the nose, mouth or eye. Flu can be a very serious illness and so those who are vulnerable, for instance the elderly, are offered flu vaccinations. There is a new vaccination every year because the virus is continuously mutating into new strains.

Tobacco mosaic virus

The tobacco mosaic virus infects tobacco and other closely related plant species, such as tomatoes and peppers. It is transmitted by contact between plants, either naturally or through the hands of farmers. It infects the of plant leaves and changes their colour from green to yellow or white in a mosaic pattern. It can also make leaves crinkle or curl up.

This reduces the plant's ability to and grow properly, which reduces the crop for farmers. There is no cure, so farmers must try to reduce the infection to their crops or attempt to reduce the spread of the virus.

Tobacco mosaic virus is used by scientists as a model organism in order to help them understand the spread of diseases.

HIV/AIDS

stands for Human Immunodeficiency Virus. It is an example of a sexually transmitted infection (STI). This infection is transmitted by body fluids, often during unprotected sex, but also through cuts and injecting drugs using shared needles. Immediately after infection, people often suffer mild flu-like symptoms. These pass and people might not know they are infected for some time.

stands for Acquired Immune Deficiency Syndrome. Months or years after infection, the HIV virus becomes active and starts to attack the patient's immune system. HIV at this point has become AIDS.

There is no cure for HIV /AIDS although many scientists are trying to find one. Currently, infected people are given , which can slow the development of AIDS.

A map showing the percentage of global population with AIDS
Figure caption,
Percentage of global population with AIDS

Bacterial diseases

Not all bacteria are , which cause disease. Many , like those found in the intestines, are useful. All bacteria are so do not have a . Unlike viruses, they are cells but they are too small to be seen without a microscope.

Population growth of bacteria

In the correct conditions - with warmth, moisture, nutrients - bacteria can multiply rapidly. The human body can provide these conditions, eg in a cut. Each bacterium may divide every 20 minutes in ideal conditions.

So, after one hour a single bacterium could have reproduced to give eight bacteria.

Diagram of how quickly bacteria can replicate within an hour

Bacteria will only divide this rapidly when conditions for growth are perfect. Eventually nutrients and space start to run out and waste products from the bacteria poison and kill them.

Salmonella

Salmonella is a of that cause food poisoning. Symptoms of food poisoning include abdominal cramps, vomiting and . It is often found in unhygienic kitchens, undercooked foods such as meat, eggs and poultry, or the same foods that have not been reheated properly. To prevent the spread of salmonella in the UK, all poultry are against it. Cooking food thoroughly, after preparing it in hygienic conditions, is the best way to avoid illness.

Greg James describes the effects of bacterial growth and how to prevent foodborne illness

Crown-gall disease

Agrobacterium is a genus of bacteria that causes tumours in plants. Agrobacterium is a Gram-negative type bacterium. The tumours it causes are called galls and are thought to be produced when a plasmid from the bacterium transfers DNA into the host cells. The bacterial DNA that is transferred into the host genome carries the genes to make the gall. The tumour often grows at the junction between the roots and stem (the crown) of the plant. Many varieties of plants are affected, including grape vines.

Protist diseases

are a group of microorganisms that have features that belong to animals, plants and . Some are like animals, others more like plants and some, called moulds, are closest to fungi. They are all , which means they have a .

Malaria

is spread by mosquitoes which carry the plasmodium protist. These are often found in areas with higher temperatures like Africa, Asia, and South and Central America, but not the UK. Mosquitoes suck blood containing the protists from an infected person. They pass the protist to other people they suck blood from. The mosquitoes do not become ill and are called because they transmit the disease.

The symptoms of malaria include a fever, sweats and chills, headaches, vomiting and . Damage is also caused to the blood and liver. After decades of research scientists developed the first malaria vaccine in 2021. Infection continues to be reduced by stopping individuals from being bitten. People sleep under mosquito nets and wear insect repellent to avoid bites. are also taken, which treat the symptoms and can prevent infection.

Fungal diseases

Not all cause disease. is a single-celled fungus that is economically important because we use it to make some bread and beer. Not all fungi are single-celled. Some, such as mushrooms, are multicellular and are much larger. Their cells are still tiny, like yeast cells, but there are many more of them. Fungal cells have a and so are .

Athlete's foot

Athlete's foot is caused by a fungus
Figure caption,
Athlete's foot is caused by a fungus

Athlete's foot is a rash caused by a fungus that is usually found between people's toes. It causes dry, red and flaky or white, wet and cracked skin. It is often found in communal areas like swimming pool changing rooms or gyms. It is transmitted by touching infected skin or surfaces that have been previously contaminated. It is treated by .

Ash dieback

Image of an ash tree that has been destroyed by a fungal disease
Figure caption,
Ash dieback causes the infected tree to wither and die

Ash dieback is a fungal disease which causes ash trees to lose their leaves, develop brown patches on their bark, and eventually die. It is caused by spores carried by the wind, as well as direct or indirect contact with contaminated plants. It was first reported in Poland in 1992 and arrived in the UK in 2012. It kills up to 90 per cent of ash trees, and so far is incurable and uncontrollable.

The spread of ash dieback was covered on in March 2016.