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Boris Johnson: Send in YOUR questions
It comes after several of his top team left their jobs in protest at his leadership.
His plan is to stay on as PM until a new leader is chosen - although this might take several months and its not clear that Members of Parliament will support that.
It's been a hectic and confusing few days for the government - and for everyone trying to keep up with events.
We want to try to answer as many of your questions as possible, so if you have a question about what is happening or what will happen next, you can put it in the comments below.
We'll ask a 大象传媒 politics expert to give you some answers.