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John Inverdale is joined by Jeremy Guscott and Andy Nicol for the Calcutta Cup clash between Scotland and England at Murrayfield.

Defending champions England come into the 2012 Six Nations off the back of a chastening six months in which they suffered embarrassment both on and off the pitch. A dismal World Cup campaign saw their players make the front page of the papers as much as the back pages due to a string of unsavoury incidents in New Zealand. It ultimately led to Martin Johnson losing his job as head coach, and temporary incumbent Stuart Lancaster has picked a hugely-revamped squad for the Six Nations.

Scotland also had a miserable World Cup, exiting at the group stage for the first time in the tournament's history. Their performances in last year's Six Nations were not much better, and they only avoided the wooden spoon with a victory over Italy in the last round of matches.

Commentary comes from Andrew Cotter and Brian Moore.