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INSIDE HEALTH 鈥� Programme 6.

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TX:听 07.08.18听 2100鈥�2130

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PRESENTER:听 MARK PORTER

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PRODUCER:听 FIONA HILL

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Porter

Hello, coming up in the next half hour:听 Steroid creams and the hazards of over-use for conditions like eczema.听 And pulmonary hypertension 鈥� raised pressure in the circulation around the lungs, an oft missed cause of breathlessness.

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Clip

About a year ago I started to feel really breathless and I had a squeak.听 And I went to the doctors and I was diagnosed with a chest infection.听 But it never went away.

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Porter

More about Lorraine鈥檚 breathing difficulties later.听 But first a new initiative that is coming to a GP surgery near you, if it hasn鈥檛 arrived already.

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Social prescribing is where doctors or other members of the primary care team try and help patients by referring them to a range of local, non-clinical services. 听Anything from exercise programmes at a football club, to being given an allotment to look after. 听And it is being taken very seriously.

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NHS England has highlighted social prescribing as one of 10 key strategies for reducing pressures on general practice. 听And the Royal College of GPs has called for every surgery to have access to a dedicated social prescriber.

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So, what can patients expect? 听And how might social prescribing help them?听 Inside Health listener Arabella was referred by her GP.

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Arabella

I鈥檝e a long history of being a mental health service user and I鈥檇 had various experiences of burnt out but this was a particularly severe mental health breakdown.听 I have Asperger鈥檚 Syndrome but this time it was combined with post-traumatic stress disorder and chronic fatigue.听 So, I was really quite debilitated and it had a huge effect on my life 鈥� I wasn鈥檛 able to work at that time and I was going to need to review everything.

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Porter

Arabella鈥檚 GP surgery had a social prescribing support worker called Diane.

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Arabella

We talked about activities that I could start doing.听 I鈥檇 become quite isolated.听 So, we looked at interests and I鈥檇 always used to sing and so I was willing to consider joining a choir again.听 And we found Bath Community Gospel Choir and that seemed like a good idea.听 And I think what was really crucial about the session is that we talked about everything 鈥� how I would get there, how I would book it, what would happen if it was a disaster, how I鈥檇 make myself go a second time.听 The kind of things that you can鈥檛 necessarily work out for yourself when your executive functioning鈥檚 pretty poor.听 So, we really did a dress rehearsal of it and that made it possible for me to go.

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Porter

The next sessions focussed on how Arabella could get help with legal and financial issues, as well as returning to work, and what work that might be 鈥� all very different from sort of help she鈥檇 had previously from the NHS.

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Arabella

In the past practitioners had been very helpful but they鈥檇 always seen me as a mental health service user or they鈥檇 seen me as somebody who was unwell.听 Whereas with Diane she always saw me as somebody who was on a journey to getting much better and to progressing myself.听 We always looked at what my natural interests were and we grew those.听 So, it was very much about a person-centred approach which helped me identify what I loved and what moved me and connected me to the services and the activities in my local community where I could go and engage in those things just as myself, not as a service user or somebody who was unwell.

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Porter

And Arabella鈥檚 experiences are typical of many.听

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Dr Marie Polley is Senior Lecturer in Health Sciences at the University of Westminster and Co-chair of the recently formed Social Prescribing Network.

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Polley

A person may come to you, as a GP, and actually you may realise that they鈥檙e isolated or lonely or there鈥檚 something more behind their depression or they need support coping with a long-term condition or actually it鈥檚 something out of your domain and that they don鈥檛 need to go and see a consultant or be prescribed medication, they need other support.听 So, at that stage you could actually refer them to somebody that we call a link worker and this is a non-clinical person who is trained in motivational interviewing, in really good listening, building rapport, trust, they don鈥檛 speak with medical jargon, they鈥檙e not viewed as a GP that鈥檚 way up there.听 And they spend an hour with a person unpacking what鈥檚 actually the situation and what support they need.听 Just as you鈥檝e heard with Arabella what actually have they enjoyed doing, where have they got to now, where would they like to get to and how can they be supported to do that.听 And then that link worker makes a referral on behalf of the patient to an organisation, a voluntary community sector organisation or social enterprise and actually is helping find what鈥檚 in their local community that can support them in the most appropriate way.

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Porter

We heard from Arabella there that she ended up at a choir, but what sort of groups are people being referred on to, can you give us an idea of the spectrum?

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Polley

Yeah, I think there鈥檚 quite a few different broad groups.听 So, you鈥檝e got a whole area of nature, health and wellbeing which is helping people get into horticulture 鈥� gardening, getting out into the environment and being physically active whilst they do it and connecting with nature, that could be walking with a group of people around the park, that could be getting out into more of the wilder parts of the country or just in community gardening projects.听 You are with people that are also interested in what you鈥檙e interested in, so naturally you form relationships and connections with people in your local community that are always there and always will be there.听 It could be something that鈥檚 more art based 鈥� culture and wellbeing.听 It could be knit and natter where you like knitting or crocheting and you do that with a group of people.听 So, there鈥檚 lots of different approaches to supporting people but it鈥檚 finding the thing that brings that person happiness and joy because then they鈥檒l keep going back to do it.

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Porter

What about the more standard holistic considerations?听 Things like fitness, for instance, the conventional thing might be that we get people to join a gym or a health club or a sports club, tennis, squash club, whatever 鈥� does that sort of thing fall under this umbrella too?

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Polley

Yeah, it that鈥檚 the thing that the person wants to do.听 It鈥檚 not about doing something that鈥檚 different to what exists, it鈥檚 about saying what exists in the community, what assets are already there, how do we connect people to these assets and how do we bring that joy back to people鈥檚 lives when they鈥檝e had a really, really difficult time.听 And sometimes that鈥檚 not by prescribing medicines, although this is not an alternative to medicine.听 You know, Mark, you鈥檝e got patients that are may be on many different types of medications and they have complex issues.听 So, it鈥檚 about saying well if we can support you mentally, psychologically, we can bring some happiness back, that will have a positive effect on your physical functioning.听 And when you start to look at a person as a person then actually what you get is a synergistic effect.

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Porter

What鈥檚 happening at the moment across the NHS in the UK 鈥� how widespread is social prescribing?

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Polley

When Dr Michael Dixon and myself set up the Social Prescribing Network we set a conference up in January 2016 and word of mouth spread and actually we had a 100 people there with a waiting list and from now we鈥檝e got 1800 people in our Social Prescribing Network.听 And we鈥檝e been working closely with NHS England and in their 10-year strategy coming up personalised care is now a really important part and using social prescribing to actually support people in the ways that they need.

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Porter

And is this typically something that starts in primary care in the general practice surgery or can it happen elsewhere as well?

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Polley

Yeah, we focused on primary care to begin with, I mean Dr Michael Dixon is a GP, but actually what we鈥檙e seeing now is a broadening of people that are referring into link workers.听 So, it could be sources within the local authority, fire service do safe and well visits and they are trusted people getting into people鈥檚 homes and they鈥檙e seeing the state that people live in and they can identify potential loneliness and refer to a link worker.听 We鈥檙e working to look at how this works with social care.听 There鈥檚 loads of people that could refer in, it鈥檚 becoming very broad now.

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Porter

And looking at the research can you demonstrate measurable reductions in demand 鈥� GPs鈥� time, attendances at hospitals etc?

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Polley

Yes, some research that I did at the University of Westminster with my research group, we led a collaboration of academics and we looked at all the research that we could find on social prescribing and we found that, on average, there was a 24% reduction in appointments to GP surgeries, there was a similar reduction in people attending A&E after a scheme had been set up 鈥� a social prescribing scheme 鈥� and there was also something around 28% reduction in unplanned admissions to hospitals.听 So, actually if that was a drug, Mark, people would be biting your hand off to prescribe it.

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Porter

Will we have universal access soon, do you think?

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Polley

I think fast forward 10 years I think that there will be universal access to social prescribing and that it will be embedded within the medical profession and I think it will be embedded in local authorities and social care.听 That will only work, Mark, if everybody realises that it鈥檚 the voluntary community sector that are the real gem in all of this because they鈥檝e been supporting people in the way that鈥檚 very bespoke and appropriate for years and years and years and they鈥檝e always been the poor relation at the table.听 So, if we don鈥檛 invest in the voluntary sector there won鈥檛 be social prescribing in 10 years鈥� time and that鈥檚 the message from the social prescribing network.

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Porter

Dr Marie Polley.听 More details, as ever, on the Inside Health page of the Radio 4 website, where you can also find details of how to contact us.听 Tessa got in touch about her daughter.

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Tessa (read)

Please, please, please investigate topical steroid addiction. 听My daughter is now in her twenties and has had eczema since early childhood. 听From her teens she鈥檚 been on a downward spiral, with increasing use of steroid creams and ever decreasing effect. 听Earlier this year she went 鈥渃old turkey鈥� and came off the steroid creams and she鈥檚 suffering horribly with her skin.

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Porter

Steroid creams and ointments like hydrocortisone, clobetasone and betamethasone are used to treat a number of skin problems. 听Overuse and misuse are recognised problems that can lead to issues on stopping treatment.听 Although doctors prefer the term topical steroid withdrawal syndrome rather than addiction.

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Tony Bewley is Consultant Dermatologist at Bart鈥檚 Health in London.

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Bewley

The problem with the word addiction is that it implies a dependency, it implies that there is some kind of drive, compulsion, to use the steroid ointments or the steroid creams and that鈥檚 not the case.听 What is the case is that patients who get this problem find that when they withdraw from using their steroid ointments that they get a particular series of symptoms which can be really quite severe but it鈥檚 without that compulsion, that need, that is implicit in the term addiction.

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Porter

Our listener talks about bright red skin, burning pain, itching 鈥� terrible itching 鈥� is that typical of what happens in this syndrome?

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Bewley

Absolutely.听 It鈥檚 usually redness of the face and with redness of the face you get burning, itching, pain.听 It doesn鈥檛 have to be the face it can be any part of the body.听 And the reason for this is that one of the ways that steroids work is by constricting blood vessels, in other words making blood vessels get narrow.听 And that gives you a certain amount of pallor, so a certain amount of loss of pinkness of the skin.听 And then when you withdraw the steroid in some patients the blood vessels don鈥檛 just go back to their normal diameter they get even wider, which gives you a certain amount of pinkness, a certain amount of flushing.听 Now along with that patients will often get pain, burning, itching.听 Also, because the blood vessels dilate when the steroids are withdrawn in this group of patients, the blood vessels can get a bit leaky and can get a bit pro-inflammatory and that can lead to spots and pustules, almost like an acne rash.听 And they can also be itchy and also a bit painful.

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Porter

Our listener鈥檚 daughter had eczema but presumably this can happen to any skin condition where you鈥檙e using steroids?

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Bewley

Sadly, it鈥檚 not that rare and we see this in dermatology clinics reasonably often.听 It is really important that any steroid that is given to patients is carefully used and it鈥檚 used on the affected areas not on the unaffected parts of the skin and it鈥檚 only used whilst the skin disease is active.听 And when the skin disease gets less active or resolves then the steroids are withdrawn and control of the problem, whatever the problem might be with the skin, is maintained with other agents like emollients and soap substitutes to try and generate better barrier function of the skin.

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Porter

So, what you鈥檙e saying is that we should try and reserve the steroids for treating the flare-ups, for getting things under control but when we get good control you maintain that control in between with the basic skin measures like moisturisers etc.听 But I think there鈥檚 a lot of patients out there, I mean we鈥檙e talking about patients using it inappropriately here, a lot of them are being inappropriately prescribed it as well.听 I can imagine there鈥檚 a lot of patients who鈥檝e got quite strong steroids on repeat prescribing and they鈥檙e not being as monitored perhaps as closely as they should be.

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Bewley

Yeah, I wouldn鈥檛 want to be too hard on healthcare professionals but I think that鈥檚 right, I think that if you are prescribing topical steroids it鈥檚 important to monitor the progress of whatever the skin condition is.听 And also, to make sure that the steroid is the right one for the right place.

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Porter

Does it matter how you come off the cream, if you鈥檙e ending a treat鈥�. do we need to reduce the steroid cream slowly, for instance?

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Bewley

Firstly, it鈥檚 really important to be clear that this happens rarely, so steroids are used very effectively and very well in the vast majority of patients but sometimes it can go wrong and the steroid withdrawal syndrome is treatable, it doesn鈥檛 last forever and there are things that you can do about that.听 And it鈥檚 really important that the diagnosis is made, that this is topical steroid withdrawal syndrome, and that the topical steroids are then stopped and then that topical steroid withdrawal syndrome symptoms are treated because they鈥檙e different from the original dermatitis.

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Porter

And how would you manage that as a dermatologist?听 Let鈥檚 assume we鈥檝e got the diagnosis, we鈥檝e made the mistake for whatever reason, now we鈥檝e got a problem, how do we manage it?

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Bewley

Well the great thing is that the steroid withdrawal syndrome, the topical steroid withdrawal syndrome, will get better spontaneously anyway once the steroids are stopped.听 But it can take quite a long time.听 So, the treatments that we use are aimed at trying to expedite that and that means, first of all, establishing good barrier function of the skin, stopping the use of the steroids that is generating the problem and using, if necessary, another anti-inflammatory.听 And the other anti-inflammatory could be topical calcineurin inhibitor cream or ointment and/or it could be something that鈥檚 used systemically, in other words a tablet.听 And the tablets that we use are usually tetracyclines.听 Now in this situation we tend to use tetracyclines in the lower dose as anti-inflammatories.听 So, the combination of establishing a good barrier function of the skin, stopping the steroids, using, if necessary, a different anti-inflammatory and using something from the inside out, in other words a tablet, usually a tetracycline, that usually makes the steroid withdrawal syndrome get better reasonably quickly.

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Porter

Tony Bewley.听 And that alternative cream, he mentioned, was a calcineurin inhibitor such as tacrolimus, more details on the website.

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Now, blood pressure. 听We all need it, but too much can be damaging to health. 听In what way depends on which part of our circulation is affected. 听It can be broadly divided into two circuits.

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One, the systemic circulation pumps oxygen and nutrients around the body to our muscles and tissues.听 And the other, the pulmonary circulation takes de-oxygenated blood returning from the systemic circuit and pumps it through the lungs.

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Too high a pressure in the main systemic circuit is often symptomless but increases the risk of problems like an early heart attack or stroke.听 However, high pressure in the lung circuit causes different problems. 听Called pulmonary hypertension it tends to put the heart under strain and cause breathlessness. 听But because you can鈥檛 measure pulmonary blood pressure with a cuff on the arm, it is much harder to spot.

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There are a number of causes of this type of raised pressure, ranging from diseases of the lungs to blood clots, but in pulmonary arterial hypertension (PAH) it is caused by constriction of the blood vessels. 听This narrowing of the arteries making it difficult for the heart to pump blood through the lungs leading to breathlessness.

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Which is what happened to Lorraine as she explained to Inside Health鈥檚 Dr Margaret McCartney.

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Lorraine

About a year ago I started to feel really breathless and I had a squeak.听 And I went to the doctors and I was diagnosed with a chest infection.听 But it never went away but it was never there all the time.听 And on the 1st January this year I was diagnosed with Australian flu which luckily for me 鈥� I know this sounds, why would you want the flu because it was horrendous 鈥� highlighted the problem.听

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McCartney

Lorraine worked a busy shift in a hospital emergency department, felt very unwell and went to her GP who measured the oxygen levels in her blood.

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Lorraine

It was sitting at 75.

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McCartney

That鈥檚 quite low.

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Lorraine

Very low and she鈥檚 like 鈥� how did you get here?听 And I goes 鈥� Well I drove.听 She went 鈥� You鈥檙e going in an ambulance.听 And I went 鈥� I鈥檝e just finished working at the hospital.

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McCartney

You were working at that point?

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Lorraine

Yeah, I work in A&E.听 And I says 鈥� We鈥檙e minus 44 beds, I can鈥檛 go back, I cannot go back.听 She was 鈥� No, you鈥檙e going back.

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McCartney

Lorraine鈥檚 experience is unfortunately typical.听 Historically it has taken around two and a half years from the onset of symptoms to reach an accurate diagnosis.听 The latest UK data shows that hasn鈥檛 changed.听 The condition is rare and easily confused with other disorders and that means it鈥檚 hard to pick up quickly.听

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Dr Colin Church at the Pulmonary Hypertension Unit at the Golden Jubilee.

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Church

These patients are often 鈥� been going to the GP or up to the hospital clinics for a number of years with these symptoms and it鈥檚 characterised by looking okay but when the patient gets up and exerts himself that鈥檚 when the symptoms really hit and that鈥檚 when they become breathless, walking up a flight of stairs suddenly they can鈥檛 manage that, they have to stop halfway up a flight of stairs, they can鈥檛 carry the bags that they used to be able to get from the shops, they鈥檙e struggling with this.听 And as the diseases progresses they might feel a bit faint when they鈥檙e exerting themselves and in some circumstances they actually black out and collapse and that鈥檚 a very worrying sign and that鈥檚 really a sign that鈥檚 suggesting that the heart is really struggling at that point.

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Lorraine

Because I鈥檇 seen so many doctors I thought I was actually going off my head because everybody kept saying to me 鈥� it鈥檚 viral 鈥� until I came to Clydebank and went to the Cath Lab.听 And was confirmed.听 And although I was devastated I was relieved because then I knew what was wrong and I wasn鈥檛 going off my head.

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McCartney

The Cath Lab that Lorraine is referring to is where the gold standard diagnostic test Right Heart Catheterisation takes place.

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Church

That involves directly measuring the pressure within the lungs using a catheter that鈥檚 put through a vein in the neck and we can measure the pressure at various points along the journey through the pulmonary circulation.听 And in fact, you鈥檝e come on a day where we鈥檙e actually doing the Right Heart Catheterisation procedures and my colleague, Dr Martin Johnson, is doing that today and we can go along and see the patient getting that done.

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McCartney

So, we鈥檝e come upstairs with Dr Colin Church to the Cath Lab.听 Colin, what鈥檚 happening just now?

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Church

So, just now the patient鈥檚 been brought into the Cath Lab and is now lying on the table and is being prepped so that we can get access to the pulmonary circulation.听 And the way we do that we use an ultrasound machine to identify the main vein in the neck and through that vein we insert a small plastic sheath which then gives us an access port into the circulation.听 What we鈥檒l see later on is once we鈥檝e done that is that the pulmonary artery catheter will be inserted through that sheath and then advanced into the pulmonary circulation into the lungs.

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McCartney

And that鈥檚 where you can take the pressure readings of the blood pressure inside the鈥�

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Church

And that鈥檚 exactly where we make the direct measurements of the pulmonary pressures.

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McCartney

There鈥檚 a busy team behind the glass screen in front of me.

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Church

So, we鈥檝e now got the sheath into position and we鈥檝e now flushed the catheter through and we鈥檙e ready to introduce the pulmonary artery catheter into the patient through the sheath.

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McCartney

After what seems like a very short time the team reach the crucial pulmonary artery.听 We can see it on a screen.听

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Church

We鈥檝e now moved it up further and you can see we鈥檙e now into the pulmonary artery.

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McCartney

Just as it鈥檚 being pushed through further on through the heart.

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Church

That鈥檚 right, so we just manually push it through and you can see the pressure wave form has changed.听 And this is really the critical measurement.听 So, here we have three readings 鈥� we have the systolic pulmonary artery pressure, then the diastolic pulmonary artery pressure and then the mean point pulmonary artery pressure.

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McCartney

So, that鈥檚 the highest, the lowest and 鈥� then the mean.

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Church

In the middle, if you like.听 And the mean pulmonary artery pressure is the diagnostic test, so it has to be above 25 for the diagnosis of pulmonary hypertension.听 And, as you can see in this patient, that it鈥檚 reading 40 millimetres of mercury, so this patient does have pulmonary hypertension.

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McCartney

This Right Heart Catheterisation that we鈥檝e been hearing about, how did you find having that done?

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Lorraine

Painless and I just lay on the table and I think I actually fell asleep at one point because I was just so relaxed.听 And then obviously got the results that afternoon.

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McCartney

So, you did well, you came in under your own steam just now鈥�

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Lorraine

I did.

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McCartney

鈥�even though you鈥檙e hooked up to oxygen and what looks like a relatively heavy oxygen canister as well.

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Lorraine

Pretty heavy.听 And I鈥檝e only got it on because I was a wee bit anxious because normally during the day I don鈥檛 have it on, I only sleep with it at night.听 And if I exert myself I do put it on.听 But it鈥檚 changed my life around 鈥� I鈥檓 here, it鈥檚 on.

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McCartney

So, does it help you to do a bit more?

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Lorraine

Yes, it does, definitely.听 I can do my shopping.听 I cannot do housework.

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McCartney

Well, that鈥檚 okay.

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Lorraine

But that鈥檚 no shame.听 But I鈥檝e got good support 鈥� I鈥檝e got a husband who鈥檚 done everything and I鈥檝e got good friends and family, so I鈥檓 very [indistinct word].

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McCartney

You鈥檝e also got a pump there, you鈥檝e got that in a wee bag there.

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Lorraine

Yeah, my wee [indistinct word] pump, my wee magic pump.

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McCartney

Tell me about that.

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Lorraine

I make up the medication and it comes through this Hickman line, which is just attached, all hidden, you can鈥檛 see anything.

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McCartney

So, I wouldn鈥檛 have known you鈥檝e got anything under it at all, so it鈥檚 under your top that you鈥檙e wearing, just a wee port, a wee catheter that鈥檚 gone in under your skin.

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Lorraine

And it comes out and then it goes in to there.

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McCartney

The pump is tucked inside a little bag, very unobtrusively, and is delivering Lorraine鈥檚 medication night and day.听 Over the last decade new drug combinations have been developed to help the treatment of this condition.

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Church

They are principally designed as pulmonary vasodilators, so what that means is they are drugs that will allow the muscle within the small arteries to relax and open up the blood vessels within the lungs.听 I mean if you look at the registries of patients now and historically patients鈥� survival was not very good, less than two years.听 Now we still unfortunately don鈥檛 have a cure but we are, on average, around seven years now for survival.听 But that leaves an enormous amount of scope to improve this situation and we are far from obtaining a cure for this condition.

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McCartney

There are several forms of this disease 鈥� some people inherit it but for others the cause is unknown.听 One big puzzle is why women make up 80% of the idiopathic or unknown cause form of the disease.听 Researchers are sure it鈥檚 to do with hormones but there鈥檚 a further complication.

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Church

There is a slight oestrogen paradox, if you like, where it鈥檚 more common in women but actually women seem to have a slightly less severe disease.听 And if you also look at animal models or pre-clinical models of pulmonary hypertension oestrogen seems to actually be protective in the pulmonary circulation.听 So, there seems to be a disconnect between what we think oestrogen should do and it should be helpful as to what we see in real life, where women seem to be more predisposed to this condition.

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McCartney

And age groups that are affected?

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Church

Age groups 鈥� so again this is changing field.听 If we look back 20 years the average age was around mid-30s.听 The more recent registries in the US, Europe and indeed in the UK registry we鈥檙e now seeing the demographic switching to the mid-50s.听 And in fact, in the UK there鈥檚 over 20% that seem to fall in the 60-69-year group as well.听 So, there鈥檚 a significant change in the demographics.

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Lorraine

I know it鈥檚 a life shortening illness but I don鈥檛 know how long that is because I don鈥檛 want to live to that expectation, I just want to take every day as it comes.听 Walking now is a nightmare but I鈥檓 getting there because I just have to think you can either lie down and give up or make the most of it.听 And I鈥檓 choosing the second option 鈥� making the most of it.

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Church

This is a life threatening condition, it鈥檚 a life shortening condition but it鈥檚 still a rare condition and I don鈥檛 want everyone out there thinking that just because they鈥檙e a bit breathless when they walk up a flight of stairs that they necessarily have pulmonary arterial hypertension but it鈥檚 just to bring to the attention that this might be a possibility and there are treatments available that if you do have this condition we can make things better.听 And many patients live with this condition and live normal lives with this condition, even though they might have quite advanced therapies such as intravenous lines that are delivering life saving drugs to them as well.

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Porter

Dr Colin Church and Lorraine talking to Margaret McCartney at the Golden Jubilee National Hospital in Clydebank.

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That鈥檚 it for this programme, and this series. 听Please do send in your ideas for items you think we should cover. 听We will be back in September, until then goodbye.

听

ENDS