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Lenny Kaye, Patti Smith’s guitarist, explains how the quest for new guitar sounds has driven the history of popular music, from Les Paul’s first guitar to Bo Diddley’s tremolo, Duane Eddy’s whammy bar, Keith Richards’s fuzz pedal, The Who’s feedback, The Byrds’ 12-string, Hendrix’s wah-wah pedal, Uli Roth and Van Halen’s shredding, The Edge’s digital delay, Ry Cooder’s slide, and KT Tunstall and Ed Sheeran’s looper pedals. With Duane Eddy, Roger McGuinn, The Edge, Bonnie Raitt, Seasick Steve, KT Tunstall, Joe Bonamassa, Uli Roth, Vernon Reid, Heart’s Nancy Wilson, The Runaways’ Lita Ford and producer Shel Talmy.