Mitochondria
Melvyn Bragg and guests discuss the power-packs within cells in all complex life on Earth: they are absolutely central to the way that cells work and the way we live.
Melvyn Bragg and guests discuss the power-packs within cells in all complex life on Earth.
Inside each cell of every complex organism there are structures known as mitochondria. The 19th century scientists who first observed them thought they were bacteria which had somehow invaded the cells they were studying. We now understand that mitochondria take components from the food we eat and convert them into energy.
Mitochondria are essential for complex life, but as the components that run our metabolisms they can also be responsible for a range of diseases – and they probably play a role in how we age. The DNA in mitochondria is only passed down the maternal line. This means it can be used to trace population movements deep into human history, even back to an ancestor we all share: mitochondrial Eve.
With
Mike Murphy
Professor of Mitochondrial Redox Biology at the University of Cambridge
Florencia Camus
NERC Independent Research Fellow at University College London
and
Nick Lane
Professor of Evolutionary Biochemistry at University College London
Producer Luke Mulhall
Last on
Featured
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Links and further reading
CONTRIBUTORS
at University College, London
at University College, LondonÌý
at the University of Cambridge
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READING LIST
Guy C. Brown, The Energy of Life (Flamingo, 2000)
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David Goodsell, The Machinery of Life (Springer, 2009)
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Geoffrey E. Hill, Mitonuclear Ecology (Oxford University Press, 2019)
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Nick Lane, Power, Sex, Suicide: Mitochondria and the Meaning of Life (Oxford University Press, 2018)
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Nick Lane, The Vital Question: Energy, Evolution, and the Origins of Complex Life (W. W. Norton, 2015)
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Nick Lane, Transformer: The Deep Chemistry of Life and Death (W. W. Norton, 2022)
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Siddhartha Mukherjee, The Song of the Cell: An Exploration of Medicine and the New Human (Bodley Head, 2022)
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Immo E. Scheffler, Mitochondria (Wiley, 2007)
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RELATED LINKS
Broadcasts
- Thu 1 Jun 2023 09:00´óÏó´«Ã½ Radio 4
- Thu 1 Jun 2023 21:30´óÏó´«Ã½ Radio 4
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