Could gene therapy cure alcoholism?
Researchers say gene therapy, currently being trialled in patients with Parkinson鈥檚 disease, could dramatically reduce chronic heavy drinking.
A form of gene therapy, that is being trialled in patients with Parkinson鈥檚 disease, might provide a potential one-off treatment for severe alcohol addiction.
A study of rhesus macaque monkeys that were predisposed to heavy drinking found that by implanting a gene into their brains, which effectively resets the brain鈥檚 dopamine reward pathway, their desire to consume alcohol was dramatically reduced.
Professor Kathleen Grant from Oregon Health and Science University鈥檚 National Primate Research Centre co-led the research. She told Newsday: 鈥淭hese monkeys were introduced to alcohol鈥hesus monkeys, they鈥檒l drink pretty heavily, on average about eight to ten drinks a day鈥f we took alcohol away from them, would they go back to drinking? We know that they do so we divided the group into two and one group got this gene therapy enhancement and鈥e saw that it would block the relapse drinking.鈥
(Picture: Shows a rhesus macaques monkey drinking from a can in Kathmandu, Nepal. Credit: Getty Images.)
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