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Fly-half Dan Biggar is Wales' latest injury worry for their Six Nations encounter against England at Twickenham on Saturday, 7 March.

Biggar, 30, was forced off 20 minutes into Northampton's 27-21 English Premiership defeat by Saracens on Saturday with a knee injury.

Saints boss Chris Boyd said Biggar's injury was not serious, but he must "wait and see" on any lay-off.

"I don't think it is serious," Boyd told ´óÏó´«Ã½ Radio Northampton.

"He's hyper-extended his leg in a collision and seems to be moving relatively OK.

"I don't think he's got any major structural damage from what I'm led to believe so it's one of those ones we'll wait and see."

Dragons outside-half Sam Davies trained with Wales before the France defeat and has been in Wayne Pivac's camp again in the build-up to the England game.

Davies is yet to be officially called up to the squad while uncapped Dragons wing Ashton Hewitt has also been training with Wales.

Cardiff Blues' Jarrod Evans would be the favourite to start against England if Biggar is ruled out. Evans was Biggar's deputy in the games against Italy, Ireland and France.

Gareth Anscombe is a long-term injury absentee, while Scarlets' Rhys Patchell is nearing a return after shoulder surgery. Wales also lost Gloucester's Owen Williams to a hamstring injury for the Six Nations.

On Sunday, new Wales lock Will Rowlands left the fray early as Wasps won at London Irish.

But interim Wasps head coach Lee Blackett played down any danger of Rowlands being forced out of contention to face England.

"He couldn't carry on as he had a slight knock to his knee so it was a medical decision to take him off," said Blackett.

"I don't think it's serious so hopefully he can go back to Wales and be involved in next week's game."

Biggar's injury came a day after Hallam Amos failed a late fitness test on a knee injury before Cardiff Blues lost 14-6 at Edinburgh.

Josh Adams is out of the tournament and fellow wing George North is a doubt. North is undergoing head injury protocols after he was forced off against France.

Amos returned for Blues last weekend as they beat Benetton in the Pro14.

He had not played since damaging ankle ligaments in January, but was called up by Wales boss Wayne Pivac before returning to regional action.

However, Amos limped off in the dying moments against Benetton on 23 February.

Cardiff Blues coach John Mulvihill told ´óÏó´«Ã½ Sport Wales that Amos was kept out of the Murrayfield match by the knee injury he suffered in the final minute of the Benetton game the previous Sunday.

"He's got a little bit of a knee complaint which kept him out of our performance this week, he definitely wasn't right to play this week," said Mulvihill.

"He'll be re-assessed by Wales next week and we'll go from there. He might have taken something into the Benetton game, but there was a knock towards the end."

New Scarlets signing Liam Williams has yet to play since suffering an ankle injury at the 2019 World Cup in Japan.

Amos and Williams can play wing or full-back.

Williams has been kept in the Wales camp this weekend despite his lack of game time and was not released for Scarlets' Saturday game against Munster.

Amos had been released to Blues and was initially named in their starting XV for the match at Murrayfield, but Dan Fish took his place.

Wales and Blues are also without wing Owen Lane, who suffered a "significant hamstring injury" in training ahead of the Six Nations.

Pivac has uncapped teenage wing Louis Rees-Zammit, of Gloucester, Scarlets' Johnny McNicholl, and Leicester's Jonah Holmes among his back-three options, along with Leigh Halfpenny. McNicholl, Holmes and Halfpenny can also play full-back.

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