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Coordination and control - The human endocrine system - Edexcel Human endocrine system

The endocrine system secretes hormones into the bloodstream from glands throughout the body. Hormones travel in the blood stream to specific target organs, where they have an effect.

Part of Biology (Single Science)Animal coordination, control and homeostasis

Human endocrine system

Hormones and nerves

A is a chemical substance, produced by a and carried in the bloodstream, which alters the activity of specific . An example of this is the release of the hormone adrenaline, which is released by the adrenal glands. One of its target organs is the heart, where it increases the heart rate.

Once a hormone has been used, it is destroyed by the liver.

Like the nervous system, hormones can control the body. The effects are much slower than the nervous system, but they last for longer.

The foil packaging for the contraceptive pill
Image caption,
Contraceptive pills contain hormones to reduce the chances of becoming pregnant

There are important differences between nervous and hormonal control.

NervousHormonal
Type of signalElectrical (chemical at synapses)Chemical
Transmission of signalBy nerve cells (neurones)By the bloodstream
EffectorsMuscles or glandsTarget cells in particular organs
Type of responseMuscle contraction or secretionChemical change
Speed of responseVery rapidSlower
Duration of responseShort (until nerve impulses stop)Long (until hormone is broken down)
Type of signal
NervousElectrical (chemical at synapses)
HormonalChemical
Transmission of signal
NervousBy nerve cells (neurones)
HormonalBy the bloodstream
Effectors
NervousMuscles or glands
HormonalTarget cells in particular organs
Type of response
NervousMuscle contraction or secretion
HormonalChemical change
Speed of response
NervousVery rapid
HormonalSlower
Duration of response
NervousShort (until nerve impulses stop)
HormonalLong (until hormone is broken down)

Different hormones

The glands in the body produce a range of different chemical hormones that travel in the bloodstream and affect a number of different organs in the body. The diagram below shows this in detail.

Hormones and the glands that produce them in the human body

Important hormones released into the bloodstream include ADH (anti-diuretic hormone), adrenaline and insulin.

HormoneSourceTarget organ(s)RoleEffects
ADHPituitary glandKidneysControlling the water content of the bloodIncreases reabsorption of water by the collecting ducts
AdrenalineAdrenal glandsSeveral targets including organs in the respiratory and circulatory systemsPreparation for 'fight or flight'Increases breathing rate, heart rate, flow of blood to muscles, conversion of glycogen to glucose
InsulinPancreasLiverControlling blood glucose levelsIncreases conversion of glucose into glycogen for storage
HormoneADH
SourcePituitary gland
Target organ(s)Kidneys
RoleControlling the water content of the blood
EffectsIncreases reabsorption of water by the collecting ducts
HormoneAdrenaline
SourceAdrenal glands
Target organ(s)Several targets including organs in the respiratory and circulatory systems
RolePreparation for 'fight or flight'
EffectsIncreases breathing rate, heart rate, flow of blood to muscles, conversion of glycogen to glucose
HormoneInsulin
SourcePancreas
Target organ(s)Liver
RoleControlling blood glucose levels
EffectsIncreases conversion of glucose into glycogen for storage

Master gland

The in the brain is known as a 'master gland'. It secretes several hormones into the blood in response to the body's condition, such as blood water levels. The detects changes in hormone levels and will release hormones which control the pituitary gland or other organs. The hormones from the hypothalamus and pituitary can also act on other glands to stimulate the release of different types of hormones and bring about effects.