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How can we treat disease? - OCR 21st CenturyEvaluation of treatment for coronary heart disease

Humans have used medicines for centuries. Most have come from plants and fungi, but increasingly they are being synthesised with chemical reactions.

Part of Biology (Single Science)Keeping healthy

Evaluation of different treatment methods for coronary heart disease

Drugs used alongside heart conditions and transplants can prolong life.

Evaluating the treatment methods

TreatmentAdvantagesDisadvantages
Drugs - statins to prevent build-up of material in arteriesReduce the risk of heart attack. Studies have shown a decrease in 'bad cholesterol' and an increase in 'good cholesterol'. Used to reduce high cholesterol levels that have genetic causes. May have beneficial effects on other conditions. Cheap to administer.Not suitable for people with liver disease. Some side effects. Must be taken for life. Should not be taken if pregnant or breastfeeding.
Heart transplant to replace a damaged heartImproves quality of life and can be lifesaving.Few donor hearts are available. Recovery time is long. There is a risk of rejection by the body's immune system. Expensive operation and aftercare.
Replacement heart valves to improve circulation of bloodRestore blood flow through the heart. Less risk of complications in surgery than heart transplant.Biological valves may wear out. Blood clots may stick to mechanical valves - anti-blood clotting drugs need to be taken which increase risk of further illness.
TreatmentDrugs - statins to prevent build-up of material in arteries
AdvantagesReduce the risk of heart attack. Studies have shown a decrease in 'bad cholesterol' and an increase in 'good cholesterol'. Used to reduce high cholesterol levels that have genetic causes. May have beneficial effects on other conditions. Cheap to administer.
DisadvantagesNot suitable for people with liver disease. Some side effects. Must be taken for life. Should not be taken if pregnant or breastfeeding.
TreatmentHeart transplant to replace a damaged heart
AdvantagesImproves quality of life and can be lifesaving.
DisadvantagesFew donor hearts are available. Recovery time is long. There is a risk of rejection by the body's immune system. Expensive operation and aftercare.
TreatmentReplacement heart valves to improve circulation of blood
AdvantagesRestore blood flow through the heart. Less risk of complications in surgery than heart transplant.
DisadvantagesBiological valves may wear out. Blood clots may stick to mechanical valves - anti-blood clotting drugs need to be taken which increase risk of further illness.

When deciding the most appropriate treatment, it is important to consider many factors, including: effectiveness, risks, costs to the individual and the health service, benefits to the patient and to society.