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Disease, defence and treatment – WJECAntibiotics and antibiotic resistance

Communicable diseases are caused by the spread of micro-organisms. How do they spread, and what future developments will come from the study of the immune system and the treatment of diseases?

Part of Biology (Single Science)Variation, homeostasis and micro-organisms

Antibiotics and antibiotic resistance

Different types of medicines are available to treat many different . Some medicines only treat the symptoms, whilst others cure the disease by killing the .

Antibiotics

Antibiotics are substances that slow down or stop the growth of . They are commonly prescribed medicines, examples include penicillin and amoxicillin. These can be taken to cure the disease by killing the pathogen, but are only effective against bacterial diseases, not viral ones.

Penicillin

Penicillin is an antibiotic which was discovered by Sir Alexander Fleming in 1928. He noticed that some bacteria he had left in a had been killed by the naturally occurring Penicillium .

Penicillin viewed through a microscope.
Image caption,
A bacterial cell damaged by penicillin

How do antibiotics work?

Antibiotics damage the bacterial cells but do not damage the host cells. They have the ability to cure some bacterial diseases that would have previously killed many people. Since their introduction, they have played a major role in improving health and reducing death rates around the world.

Different bacteria cause different diseases. One particular antibiotic may only work against one or a few types of bacteria. This means that a range of different antibiotics is needed for the treatment of a number of bacterial diseases.

Viral diseases

Viral diseases cannot be cured by antibiotics, because they reproduce inside the host cells.

Antibiotic resistance

Since the discovery of Penicillin in 1928, the use of antibiotics for the treatment of diseases has increased exponentially. As a result, are being overused in many ways in our world today.

Problems with antibiotics

Commonly prescribed antibiotics are becoming less effective due to a number of reasons:

  • overuse of antibiotics
  • failing to complete the fully prescribed course by a doctor
  • use of antibiotics in farming

These can lead to a reduction in the effectiveness of antibiotics, and an increase in the incidence of . These bacteria are commonly known as superbugs.

One of these superbugs is methicillin-resistant Staphylococcus aureus (MRSA). It is important that there are control measures in place to prevent the spread of this disease. These include:

  • hand washing
  • thorough cleaning of hospital wards
  • use of alcohol gels
  • MRSA screening