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Medicine in 18th- and 19th-century Britain, c.1700-c.1900 - EdexcelLouis Pasteur and germ theory

Medicine in 18th- and 19th-century Britain saw great change, especially following the publication of Louis Pasteur鈥檚 germ theory. This led to significant changes in surgery and better prevention of disease in the late 19th century.

Part of HistoryMedicine in Britain, c.1250 to the present day

Louis Pasteur and germ theory

In the 19th century, Louis Pasteur made a discovery that led to changes in all areas of medicine.

Spontaneous generation

Some people still believed in the harmful effects of or 鈥榖ad air鈥, even in the 18th century. However, this theory was rapidly becoming less convincing. Instead, scientists developed the theory of spontaneous generation. Improved meant that scientists could see Scientists observed that microbes appeared on things that had started to rot and believed that they were the product of decay.

The discovery of germs and pasteurisation

Louis Pasteur was a French scientist who specialised in chemistry and microbiology. While working at a university in Lille, he spoke with a brewer, who wanted to know more about why the drinks he made sometimes went sour. Pasteur鈥檚 experiments brought greater understanding of the process of and how to prevent it. Prevention was achieved by heating the liquid to a certain temperature, which would kill in the liquid and thereby stop it from going bad. This process became known as pasteurisation.

A swan neck flask. There are two glass tubes coming out from the top of the flask, one of which bends downwards to the table and then up again.
Figure caption,
A swan neck flask, like the ones that Pasteur would have used

Pasteur used microscopes and other instruments in his work. The swan neck flask helped him to understand more about the role of bacteria - a type of - in fermentation. When air entered the long neck, tiny particles (bacteria) were trapped in the long tube. If they could not reach the liquid, no souring took place. When the flask was tipped and the particles were able to reach the liquid, it would turn sour.

Pasteur鈥檚 findings significantly challenged the idea of spontaneous generation and he published his germ theory in 1861. Pasteur argued that bacteria were the cause of disease, but he was not able to identify the specific bacteria that caused individual diseases.

The influence of Pasteur鈥檚 germ theory

Pasteur鈥檚 ideas were not accepted in Britain straight away and many people continued to believe in the idea of spontaneous generation. However, there were some scientists who continued to research the link between bacteria and disease.

Joseph Lister, a surgeon, read Pasteur鈥檚 ideas and began to make links between bacteria and in surgery. However, Lister faced challenges proving his ideas. had become more advanced and it was possible to see bacteria using them. However, it was difficult to separate the bacteria that were causing infection from those already present.