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Medicine in 18th- and 19th-century Britain, c.1700-c.1900 - EdexcelRobert Koch and bacteria

Medicine in 18th- and 19th-century Britain saw great change, especially following the publication of Louis Pasteur鈥檚 germ theory. This led to significant changes in surgery and better prevention of disease in the late 19th century.

Part of HistoryMedicine in Britain, c.1250 to the present day

Robert Koch and bacteria

In the mid-19th century, the scientist Louis Pasteur argued that - a type of - was the cause of disease. However, he was not able to identify the specific bacteria which cause individual diseases. It was the German doctor Robert Koch who was able to successfully identify some of the different bacteria that cause common diseases.

Robert Koch鈥檚 work on bacteria

A photograph of Robert Kock working with flasks, petri dishes and scientific equipment
Figure caption,
Robert Koch in his laboratory. He is using a microscope while surrounded by circular petri dishes

Koch developed a new method of growing bacteria using in a He then used a dye to stain the bacteria so that it could be seen clearly under a Using this method, he was able to identify individual bacteria.

In 1876, Koch found the bacteria that cause Then, in 1882, he identified the bacteria that cause His discovery of the bacteria that cause followed shortly after, in 1883.

Koch鈥檚 research inspired other scientists. Their work led to the discovery of further bacteria that cause diseases, such as diphtheria, pneumonia and meningitis. Koch鈥檚 work greatly improved medicine in Britain, as doctors now understood that it was bacteria that caused the symptoms of disease, so it was the bacteria that needed to be removed.

Koch, Pasteur and the prevention of disease

Koch鈥檚 identification of bacteria did not make an immediate difference to the prevention of disease. This only happened when Pasteur took Koch鈥檚 work even further by developing other

Pasteur had read about Edward Jenner鈥檚 vaccine, which had been developed in the late 18th century. Now that the individual bacteria for specific diseases had been identified, Pasteur began work on developing further vaccines for animals and humans. He knew that to prevent each disease, a weakened dose of the disease was needed to build

Pasteur began developing animal vaccines for the diseases anthrax and chicken cholera. Then in 1885, he tested a human vaccine for rabies that saved a boy鈥檚 life after he had been bitten by a dog. This was the first successful vaccine since Jenner鈥檚 smallpox vaccine.