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Genetic inheritance - part two - EdexcelInheritance of blood groups

We inherit our sex (male or female) and blood group from our parents. Genetic disorders can also be inherited. Selective breeding occurs when humans breed plants and animals for specific characteristics. Cloning (often in plants and not in humans) makes genetically identical copies of the one parent organism.

Part of Biology (Single Science)Genetics

Inheritance of blood groups

Codominance

Some are both expressed in the same phenotype, this is called codominance.

Both codominant alleles are shown with upper case letters in genetic diagrams, but the letters used are different. For example, feather colour in hens may be white, black or speckled (it has both white feathers and black feathers).

The alleles can be shown as W for white and B for black.

There are three possible : WW, BB and BW.

There are also three possible phenotypes: WW = white, BB = black, and BW = speckled.

Codominance in chickens. Pheontypes of the three are white, black and speckled. The genotypes are WW, BB, and BW.
Figure caption,
Codominance in chickens

Blood groups

The controlling human ABO blood groups has three alleles, not just two:

  • IA and IB are not over one another
  • both are dominant over IO

This table shows the possible genotypes (alleles present) and phenotypes (blood group):

GenotypePhenotype
IA IA or IA IOA
IB IB or IB IOB
IA IBAB
IO IOO
GenotypeIA IA or IA IO
PhenotypeA
GenotypeIB IB or IB IO
PhenotypeB
GenotypeIA IB
PhenotypeAB
GenotypeIO IO
PhenotypeO

So to inherit blood group A you must receive an IA allele from one parent and either an IA or an IO allele from the other. To inherit blood group B you must receive an IB allele from one parent and either an IB or an IO allele from the other. To inherit blood group AB you must receive an IA allele from one parent and an IB allele from the other. To inherit blood group O you must receive an Io from both parents.