Monday 2nd December
Week 13
- San Francisco 49ers vs Buffalo Bills, ScheduledSan Francisco 49ersRecord: 5 wins, 5 lossesBuffalo BillsRecord: 9 wins, 2 lossesVenue: Highmark Stadium
Sunday 8th December
Week 14
- Chicago Bears vs San Francisco 49ers, ScheduledChicago BearsRecord: 4 wins, 6 lossesSan Francisco 49ersRecord: 5 wins, 5 lossesVenue: Levi's Stadium - Santa Clara, CA
Friday 13th December
Week 15
- Los Angeles Rams vs San Francisco 49ers, ScheduledLos Angeles RamsRecord: 5 wins, 5 lossesSan Francisco 49ersRecord: 5 wins, 5 lossesVenue: Levi's Stadium - Santa Clara, CA
Sunday 22nd December
Week 16
- San Francisco 49ers vs Miami Dolphins, ScheduledSan Francisco 49ersRecord: 5 wins, 5 lossesMiami DolphinsRecord: 4 wins, 6 lossesVenue: Hard Rock Stadium - Miami Gardens, FL
Tuesday 31st December
Week 17
- Detroit Lions vs San Francisco 49ers, ScheduledDetroit LionsRecord: 9 wins, 1 lossSan Francisco 49ersRecord: 5 wins, 5 lossesVenue: Levi's Stadium - Santa Clara, CA
All times are UK and subject to change. 大象传媒 is not responsible for any changes.